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PDRN Micro-Infusion System

PDRN Micro-Infusion System

Skincare that finally absorbs.

SkinOS is an at-home micro-infusion system that pairs ultra-fine cosmetic touchpoints with a PDRN serum, helping active ingredients absorb more effectively than a topical applied on its own. For smoother, plumper, more radiant-looking skin over time, without the clinic, or the complexity.

PDRN-powered. Developed with skincare experts
Gentler than a visit clinic
5 minutes. Every two weeks.
Helps active ingredients absorb better

Suited to: All skin types, including sensitive skin.

90 Day Money Back Guarantee

We're confident you'll love your results. If not, contact our team during your risk-free trial and we'll handle the rest!

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Most Serums Never Get Past the Surface

As skin matures, its outer barrier becomes less efficient at absorbing what's applied on top. That's not a product problem - it's a delivery one. A great serum can only do so much if most of it sits on the surface.

SkinOS uses ultra-fine cosmetic touchpoints to create temporary micro-channels in the skin's surface, helping a PDRN serum absorb more effectively than it would on its own. For smoother, plumper, more radiant-looking skin over time.

Designed for absorption. Gentle enough for home.

Excellent · 1,000+ Reviews · ★★★★★

What Customers Are Saying

Janet, 47
"Feels like my skin again"
"Perimenopause did a number on my skin texture and I felt like nothing was helping. This is the first thing in a while that made my skin feel hydrated and look a little more even. Comfortable and easy to use at home too."
Susan, 59
"My skin texture is just nicer"
"The lines around my mouth had been bothering me. After 5 treatments the area feels softer and my skin texture overall is just nicer. So glad I tried this."
Linda, 49
"Softened so much, especially when I smile"
"To be honest I didn't expect much. The look of the lines around my eyes has softened, especially when I smile, and my cheeks look smoother. Placed another order."
Carol, 61
"Worth being patient for"
"I almost gave up around week three because I wasn't seeing much. Glad I kept going. By the end of the full routine my cheeks felt firmer and the skin around my jaw looked a bit more lifted to me. Will repurchase"
Diana, 52
"Genuinely surprised by the difference"
"I did the full 3 months and the difference around my neck is really there. My skin looks smoother and a bit more like itself. Happy I tried it."
Margaret, 40
"My makeup sits better now"
"I'd noticed my foundation settling into the creases on my forehead. After a couple of months using this a few nights a week, the skin there feels smoother and my makeup goes on more evenly. Small thing but it made me happy."

More Than a Serum. Simpler Than a Clinic Visit.

SkinOS works in two parts. Ultra-fine cosmetic touchpoints create temporary micro-channels in the skin's outer layer - invisible, comfortable, and gone within hours. Through those channels, a PDRN serum absorbs more effectively than a topical applied on its own. PDRN (polydeoxyribonucleotide) is a salmon-derived compound widely used in skincare, valued for supporting the look of smoother, firmer, more radiant skin. A more intentional step than a serum - done privately, at home, on your own schedule.
Supports the look of firmness
Helps active ingredients absorb
Helps improve the look of texture & radiance

Why PDRN, and Why Now

A Studied Compound

PDRN is a salmon-derived compound that's been studied for years and is widely used in aesthetic skincare for its appearance benefits.

Used in Clinics Worldwide

PDRN is used in aesthetic skincare clinics across Korea and Europe to support skin quality, texture, and hydration. Clinic sessions can cost thousands of dollars.

At Home, the Smart Way

SkinOS combines a PDRN serum with at-home micro-infusion. The device helps the serum absorb more effectively than a topical alone. Five minutes, every two weeks, in your bathroom.

Built for Mature Skin

Mature skin needs more than topical moisture. PDRN is one of the few studied ingredients associated with supporting the look of skin quality, hydration, and texture as skin's natural renewal slows.

How to use your micro-infusion system

Prepare your device

Fill the chamber with one ampoule of serum, attach the single-use head, and let it sit upside down for 1–2 minutes while you cleanse.

Infuse your skin

Gently stamp the device across your face, focusing on areas of concern. The ultra-fine cosmetic-grade touchpoints create temporary micro-channels that help the serum absorb.

See your results

With consistent use, your skin can appear smoother, more radiant, and refreshed over time.

Powered by proven ingredients

Salmon PDRN

Helps support skin repair and renewal, improving the look of wrinkles, elasticity, and overall radiance.

Peptides

Support collagen and elastin, helping smooth texture and soften the appearance of fine lines and skin texture.

Niacinamide

Helps brighten the look of dark spots, even skin tone, and strengthen the skin barrier for a smoother feel.

Hyaluronic Acid

Delivers deep hydration to plump skin and reduce the appearance of dryness and dullness.

Frequently Asked Questions

The device uses ultra-fine cosmetic-grade touchpoints to gently stamp the skin's surface, creating temporary micro-channels that help active ingredients like PDRN absorb more effectively. It's a gentle method designed to enhance product absorption and help skin look refreshed, with minimal downtime

Each kit includes:6 Week Supply: 3 sterile heads and 3 serum vials, providing 3 treatments.12 Week Supply: 6 sterile heads and 6 serum vials, providing 6 treatments.Each head and serum is intended for a single application every 1-2 weeks and should not be reused.

Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and healthier overall.Because micro-infusion supports the skin’s natural renewal process, results can continue to build gradually over time.

You have 90 days to try the system. If you're not satisfied, simply contact our team within the 90-day period and we'll arrange your refund.

After each use, follow these cleaning steps, follow the below cleaning instructions:Twist off the head with the cap attached and safely dispose.Wash the chamber out with water and gentle cleanser.Let the device air dry completely, on a clean surface, before packing away.Open a brand new head and attach the head onto the device. Ensure hands are clean and don’t open the cap of the head.

Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and more radiant overall.Because micro-infusion supports the skin's natural renewal process, results can continue to build gradually over time.

Yes — the PDRN Micro-Infusion System is suitable for all skin types, including normal, dry, oily, and combination. It’s designed to be gentle and effective, even for sensitive skin. If you have specific skin concerns such as eczema, rosacea, or severe acne, we recommend consulting with your dermatologist before purchasing to ensure it’s right for you.

There’s very little downtime. You may notice mild redness or sensitivity right after application, similar to a light sunburn, which usually fades within 12–24 hours.We recommend avoiding makeup, exfoliants, and strong active ingredients (like retinol, AHAs, BHAs, or vitamin C) for the first 24 hours to allow your skin to recover and maximize results. After that, you can return to your usual skincare routine.Most people go back to daily activities immediately, with visible glow and minimal disruption.

Yes, the SkinOS Micro-Infusion System can be used on the neck and décolletage, areas often associated with fine lines and uneven texture.For the eye area, avoid direct use on the eyelids or too close to the lash line. Instead, focus on the under-eye and outer corners (crow’s feet), where the skin is thinner but can still benefit from infusion. Always use gentle pressure, follow instructions carefully, and patch test first.

We recommend a PDRN Micro-Infusion application every 2 weeks for the best results!

Rejuran is an in-clinic treatment that also uses PDRN. SkinOS offers an at-home option using the same family of PDRN ingredient in a topical serum, paired with micro-infusion to help it absorb - without injections or clinic visits.

No — PDRN (Polydeoxyribonucleotide) is derived from salmon DNA. If you have a fish allergy, we do not recommend using this system, as it may trigger a reaction.Your safety is our priority. If you have concerns about allergies or sensitivities, please consult your healthcare provider before use.

Yes, we ship worldwide. We have 5-12 day shipping times depending on your location.